Genetic Regulation of Transcriptional Variation in Natural Arabidopsis thaliana Accessions.

ABSTRACT: An increased knowledge of the genetic regulation of expression in Arabidopsis thaliana is likely to provide important insights about the basis of the plant's extensive phenotypic variation. Here, we reanalyzed two publicly available datasets with genome-wide data on genetic and transcript variation in large collections of natural A. thaliana accessions. Transcripts from more than half of all genes were detected in the leaves of all accessions, and from nearly all annotated genes in at least one accession. Thousands of genes had high transcript levels in some accessions, but no transcripts at all in others, and this pattern was correlated with the genome-wide genotype. In total, 2669 eQTL were mapped in the largest population, and 717 of them were replicated in the other population. A total

SUBMITTER: Zan Y 

PROVIDER: S-EPMC4978887 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature