Blood pressure variability and cardiovascular disease: systematic review and meta-analysis.

ABSTRACT:

Objective

 To systematically review studies quantifying the associations of long term (clinic), mid-term (home), and short term (ambulatory) variability in blood pressure, independent of mean blood pressure, with cardiovascular disease events and mortality.

Data sources

 Medline, Embase, Cinahl, and Web of Science, searched to 15 February 2016 for full text articles in English.

Eligibility criteria for study selection

 Prospective cohort studies or clinical trials in adults, except those in patients receiving haemodialysis, where the condition may directly impact blood pressure variability. Standardised hazard ratios were extracted and, if there was little risk of confounding, combined using random effects meta-analysis in main analyses. Outcomes included all cause an

SUBMITTER: Stevens SL 

PROVIDER: S-EPMC4979357 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature