Washed cell salvage in surgical patients: A review and meta-analysis of prospective randomized trials under PRISMA.

ABSTRACT:

Background

Cell salvage is commonly used as part of a blood conservation strategy. However concerns among clinicians exist about the efficacy of transfusion of washed cell salvage.

Methods

We performed a meta-analysis of randomized controlled trials in which patients, scheduled for all types of surgery, were randomized to washed cell salvage or to a control group with no cell salvage. Data were independently extracted, risk ratio (RR), and weighted mean differences (WMD) with 95% confidence intervals (CIs) were calculated. Data were pooled using a random effects model. The primary endpoint was the number of patients exposed to allogeneic red blood cell (RBC) transfusion.

Results

Out of 1140 search results, a total of 47 trials were included. Overall, the use of washed

SUBMITTER: Meybohm P 

PROVIDER: S-EPMC4979849 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature