Activated Protein C Resistance Does Not Increase Risk for Recurrent Stroke or Death in Stroke Patients.

ABSTRACT:

Background

Activated protein C (APC) resistance is the most common inherited prothrombotic disorder. The role of APC resistance in ischemic stroke is controversially discussed.

Objectives

The aim of this single center follow up study was to investigate the effect of APC resistance on stroke recurrence and survival in stroke patients.

Patients/methods

We retrospectively identified 966 patients who had had an ischemic stroke or transitory ischemic attack (TIA) and in whom laboratory tests for APC resistance had been conducted. These patients were contacted to determine the primary outcomes of recurrent ischemic stroke or death.

Results

A total of 858 patients with an average follow up time of 8.48 years were included. APC resistance did not influence cumulative i

SUBMITTER: Thaler MA 

PROVIDER: S-EPMC4980060 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature