Urinary phthalate metabolite and bisphenol A associations with ultrasound and delivery indices of fetal growth.

ABSTRACT: Growth of the fetus is highly sensitive to environmental perturbations, and disruption can lead to problems in pregnancy as well as later in life. This study investigates the relationship between maternal exposure to common plasticizers in pregnancy and fetal growth. Participants from a longitudinal birth cohort in Boston were recruited early in gestation and followed until delivery. Urine samples were collected at up to four time points and analyzed for concentrations of phthalate metabolites and bisphenol A (BPA). Ultrasound scans were performed at four time points during pregnancy for estimation of growth parameters, and birthweight was recorded at delivery. Growth measures were standardized to a larger population. For the present analysis we examined cross-sectional and repeated measur

SUBMITTER: Ferguson KK 

PROVIDER: S-EPMC4980186 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature