Exposure to coarse particulate matter during gestation and birth weight in the U.S.

ABSTRACT: Few studies have explored the relationship between coarse particles (PM10-2.5) and adverse birth outcomes. We examined associations between gestational exposure of PM10-2.5 and birth weight. U.S. birth certificates data (1999-2007) were acquired for 8,017,865 births. Gestational and trimester exposures of PM10-2.5 were estimated using co-located PM10 and PM2.5 monitors ≤35km from the population-weighted centroid of mothers' residential counties. A linear regression model was applied, adjusted by potential confounders. As sensitivity analyses, we explored alternative PM10-2.5 estimations, adjustment for PM2.5, and stratification by regions. Gestational exposure to PM10-2.5 was associated with 6.6g (95% Confidence Interval: 5.9, 7.2) lower birth weight per interquartile range increase (7.8μg

SUBMITTER: Ebisu K 

PROVIDER: S-EPMC4980266 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature