Longitudinal associations between adiponectin and cardiac structure differ by hypertensive status: Coronary Artery Risk Development in Young Adults.

ABSTRACT:

Objective

We studied the longitudinal association between adiponectin and cardiac structure and function 10 years later stratified by hypertension status.

Methods

Multicenter longitudinal study of black and white men and women that began in 1985-1986, when participants were 18-30 years old. Adiponectin was measured at year 15(2000-2001). Echocardiograms were completed at year 25(2010-2011). Participants were stratified by the presence of hypertension. Risk factor-adjusted echocardiographic variables were compared across adiponectin quintiles. Linear and quadratic regression models were also derived for risk factor-adjusted echocardiographic variables.

Results

Relative to the lowest quintile of adiponectin, participants from the highest quintile had a 6% lower LV mass

SUBMITTER: Sharma S 

PROVIDER: S-EPMC4980644 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature