The Etiology, Incidence, and Impact of Preservation Fluid Contamination during Liver Transplantation.

ABSTRACT: The role of contaminated preservation fluid in the development of infection after liver transplantation has not been fully elucidated. To assess the incidence and etiology of contaminated preservation fluid and determine its impact on the subsequent development of infection after liver transplantation, we prospectively studied 50 consecutive liver transplants, and cultured the following samples in each instance: preservation fluid (immediately before and at the end of the back-table procedure, and just before implantation), blood, and bile from the donor, and ascitic fluid from the recipient. When any culture was positive, blood cultures were obtained and targeted antimicrobial therapy was started. We found that the incidence of contaminated preservation fluid was 92% (46 of 50 cases of li

SUBMITTER: Oriol I 

PROVIDER: S-EPMC4981323 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature