Maternal Antiretroviral Therapy Is Associated with Lower Risk of Diarrhea in Early Childhood.

ABSTRACT:

Objectives

To identify risk factors, including maternal antiretroviral therapy (ART), for diarrhea in Tanzanian children exposed to HIV during the first 2 years of life.

Study design

Using generalized estimating equations, we analyzed data from a cohort of 2387 Tanzanian children exposed to HIV from age 6 weeks to 2 years, as well as data from their mothers, to determine risk factors for diarrhea in children. Mothers recorded diarrhea in a diary and reported results at visits scheduled every four weeks.

Results

Body mass index was ≥18.5 in 95.6% of mothers. World Health Organization HIV stage was 1/2 for 1255 (87.8%) mothers. ART was received by 24.3% of mothers, most initiating ART during pregnancy. At baseline (6 weeks of age) 264 (11.3%) children were infected with

SUBMITTER: Sztam KA 

PROVIDER: S-EPMC4981520 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature