Prognostic Value of NME1 (NM23-H1) in Patients with Digestive System Neoplasms: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

There is a heated debate on whether the prognostic value of NME1 is favorable or unfavorable. Thus, we carried out a meta-analysis to evaluate the relationship between NME1 expression and the prognosis of patients with digestive system neoplasms.

Methods

We searched PubMed, EMBASE and Web of Science for relevant articles. The pooled odd ratios (ORs) and corresponding 95%CI were calculated to evaluate the prognostic value of NME1 expression in patients with digestive system neoplasms, and the association between NME1 expression and clinicopathological factors. We also performed subgroup analyses to find out the source of heterogeneity.

Results

2904 patients were pooled from 28 available studies in total. Neither the incorporative OR combined by 17 studies wit

SUBMITTER: Han W 

PROVIDER: S-EPMC4982620 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature