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Clinical Activity and Quality of Life Indices Are Valid Across Ulcerative Colitis But Not Crohn's Disease Phenotypes.


ABSTRACT:

Background

Clinical activity and quality of life (QOL) indices assess disease activity in Crohn's disease (CD) and ulcerative colitis (UC). However, a paucity of data exists on the validity of these indices according to disease characteristics.

Aims

To examine the correlation between QOL and clinical activity indices and endoscopic disease activity according to disease characteristics.

Methods

We used a prospective registry to identify CD and UC patients ≥18 years old with available information on Short Inflammatory Bowel Disease Questionnaire scores (SIBDQ), Harvey-Bradshaw Index (HBI) and simple endoscopic scores for CD (SES-CD), and Simple Clinical Colitis Activity Index (SCCAI) and Mayo endoscopic score for UC. We used Spearman rank correlations to calculate corre

SUBMITTER: Taleban S 

PROVIDER: S-EPMC4982770 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature