Endocrine-specific NIR fluorophores for adrenal gland targeting.

ABSTRACT: The adrenal glands (AGs) are relatively small yet require definitive identification during their resection, or more commonly their avoidance. To enable image-guided surgery involving the AGs, we have developed novel near-infrared (NIR) fluorophores that target the AGs after a single intravenous injection, which provided dual-NIR image-guided resection or avoidance of the AGs during both open and minimally-invasive surgery.

SUBMITTER: Ashitate Y 

PROVIDER: S-EPMC4982771 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature