Prolonged Nightly Fasting and Breast Cancer Prognosis.

ABSTRACT:

Importance

Rodent studies demonstrate that prolonged fasting during the sleep phase positively influences carcinogenesis and metabolic processes that are putatively associated with risk and prognosis of breast cancer. To our knowledge, no studies in humans have examined nightly fasting duration and cancer outcomes.

Objective

To investigate whether duration of nightly fasting predicted recurrence and mortality among women with early-stage breast cancer and, if so, whether it was associated with risk factors for poor outcomes, including glucoregulation (hemoglobin A1c), chronic inflammation (C-reactive protein), obesity, and sleep.

Design, setting, and participants

Data were collected from 2413 women with breast cancer but without diabetes mellitus who were aged 27 to 7

SUBMITTER: Marinac CR 

PROVIDER: S-EPMC4982776 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature