High risk of post-infectious irritable bowel syndrome in patients with Clostridium difficile infection.

ABSTRACT:

Background

Infectious enteritis is a commonly identified risk factor for irritable bowel syndrome (IBS). The incidence of Clostridium difficile infection (CDI) is on the rise. However, there is limited information on post-infectious IBS (PI-IBS) development following CDI and the host- and infection-related risk factors are not known.

Aim

To determine the incidence and risk factors for PI-IBS following CDI.

Methods

A total of 684 cases of CDI identified from September 2012 to November 2013 were surveyed. Participants completed the Rome III IBS questionnaire and details on the CDI episode. Predictive modelling was done using logistic regression to evaluate risk factors for PI-IBS development.

Results

A total of 315 CDI cases responded (46% response rate) and 205

SUBMITTER: Wadhwa A 

PROVIDER: S-EPMC4982831 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature