Robustness quantification methods comparison in volumetric modulated arc therapy to treat head and neck cancer.

ABSTRACT:

Background

To compare plan robustness of volumetric modulated arc therapy (VMAT) with intensity modulated radiation therapy (IMRT) and to compare the effectiveness of 3 plan robustness quantification methods.

Methods and materials

The VMAT and IMRT plans were created for 9 head and neck cancer patients. For each plan, 6 new perturbed dose distributions were computed using ±3 mm setup deviations along each of the 3 orientations. Worst-case analysis (WCA), dose-volume histogram (DVH) band (DVHB), and root-mean-square dose-volume histogram (RVH) were used to quantify plan robustness. In WCA, a shaded area in the DVH plot bounded by the DVHs from the lowest and highest dose per voxel was displayed. In DVHB, we displayed the envelope of all DVHs in band graphs of all the 7 dose d

SUBMITTER: Liu W 

PROVIDER: S-EPMC4983261 | biostudies-literature | 2016 Nov - Dec

REPOSITORIES: biostudies-literature