Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing.

ABSTRACT: Prolonged unaccustomed exercise involving muscle lengthening (eccentric) actions can result in ultrastructural muscle disruption, impaired excitation-contraction coupling, inflammation and muscle protein degradation. This process is associated with delayed onset muscle soreness and is referred to as exercise-induced muscle damage. Although a certain amount of muscle damage may be necessary for adaptation to occur, excessive damage or inadequate recovery from exercise-induced muscle damage can increase injury risk, particularly in older individuals, who experience more damage and require longer to recover from muscle damaging exercise than younger adults. Furthermore, it is apparent that inter-individual variation exists in the response to exercise-induced muscle damage, and there is eviden

SUBMITTER: Baumert P 

PROVIDER: S-EPMC4983298 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature