AlgU Controls Expression of Virulence Genes in Pseudomonas syringae pv. tomato DC3000.

ABSTRACT:

Unlabelled

Plant-pathogenic bacteria are able to integrate information about their environment and adjust gene expression to provide adaptive functions. AlgU, an extracytoplasmic function (ECF) sigma factor encoded by Pseudomonas syringae, controls expression of genes for alginate biosynthesis and genes involved with resisting osmotic and oxidative stress. AlgU is active while these bacteria are associated with plants, where its presence supports bacterial growth and disease symptoms. We found that AlgU is an important virulence factor for P. syringae pv. tomato DC3000 but that alginate production is dispensable for disease in host plants. This implies that AlgU regulates additional genes that facilitate bacterial pathogenesis. We used transcriptome sequencing (RNA-seq) to characte

SUBMITTER: Markel E 

PROVIDER: S-EPMC4984547 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature