Tailoring particle translocation via dielectrophoresis in pore channels.

ABSTRACT: Understanding and controlling electrophoretic motions of nanoscopic objects in fluidic channels are a central challenge in developing nanopore technology for molecular analyses. Although progress has been made in slowing the translocation velocity to meet the requirement for electrical detections of analytes via picoampere current measurements, there exists no method useful for regulating particle flows in the transverse directions. Here, we report the use of dielectrophoresis to manipulate the single-particle passage through a solid-state pore. We created a trap field by applying AC voltage between electrodes embedded in a low-aspect-ratio micropore. We demonstrated a traffic control of particles to go through center or near side surface via the voltage frequency. We also found enhanced c

SUBMITTER: Tanaka S 

PROVIDER: S-EPMC4985646 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature