Residential proximity to traffic and female pubertal development.

ABSTRACT:

Background

Traffic-related air pollution (TRAP) has been linked with several adverse health outcomes, including preterm birth and low birth weight, which are both related to onset of puberty. No studies to date have investigated the association between TRAP and altered pubertal timing.

Objective

Determine the association between residential proximity to traffic, as a marker of long-term TRAP exposure, and age at pubertal onset in a longitudinal study of girls.

Methods

We analyzed data for 437 girls at the CYGNET study site of the Breast Cancer and Environment Research Program. TRAP exposure was assessed using several measures of residential proximity to traffic based on address at study entry. Using accelerated failure time models, we calculated time ratios (TRs) and

SUBMITTER: McGuinn LA 

PROVIDER: S-EPMC4986602 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature