Postoperative Nomogram for Predicting Cancer-Specific Mortality in Medullary Thyroid Cancer.

ABSTRACT:

Background

Medullary thyroid cancer (MTC) is a rare thyroid cancer accounting for 5 % of all thyroid malignancies. The purpose of our study was to design a predictive nomogram for cancer-specific mortality (CSM) utilizing clinical, pathological, and biochemical variables in patients with MTC.

Methods

MTC patients managed entirely at Memorial Sloan-Kettering Cancer Center between 1986 and 2010 were identified. Patient, tumor, and treatment characteristics were recorded, and variables predictive of CSM were identified by univariable analyses. A multivariable competing risk model was then built to predict the 10-year cancer specific mortality of MTC. All predictors of interest were added in the starting full model before selection, including age, gender, pre- and postoperative

SUBMITTER: Ho AS 

PROVIDER: S-EPMC4986610 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature