Systematic Review: Adverse Events of Fecal Microbiota Transplantation.

ABSTRACT:

Background

Fecal microbiota transplantation (FMT) is a microbiota-based therapy that shows therapeutic potential in recurrent or refractory Clostridium difficile infections and other intestinal or extra-intestinal disorders. Nonetheless, adverse events (AEs) remain a major challenge in the application of FMT.

Aim

To review the AEs of FMT and to address the concerns of safety during the procedure.

Methods

Publications were retrieved in the databases of Medline, Embase and Cochrane Library. AEs were classified according to their causality with FMT or their severity.

Results

A total of 7562 original articles about FMT were identified in this study, 50 of them fulfilled the inclusion criteria. Totally 78 kinds of AEs were revealed enrolled in these 50 selected publ

SUBMITTER: Wang S 

PROVIDER: S-EPMC4986962 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature