Forelimb training drives transient map reorganization in ipsilateral motor cortex.

ABSTRACT: Skilled motor training results in reorganization of contralateral motor cortex movement representations. The ipsilateral motor cortex is believed to play a role in skilled motor control, but little is known about how training influences reorganization of ipsilateral motor representations of the trained limb. To determine whether training results in reorganization of ipsilateral motor cortex maps, rats were trained to perform the isometric pull task, an automated motor task that requires skilled forelimb use. After either 3 or 6 months of training, intracortical microstimulation (ICMS) mapping was performed to document motor representations of the trained forelimb in the hemisphere ipsilateral to that limb. Motor training for 3 months resulted in a robust expansion of right forelimb represe

SUBMITTER: Pruitt DT 

PROVIDER: S-EPMC4987250 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature