Delayed mortality effects cut the malaria transmission potential of insecticide-resistant mosquitoes.

ABSTRACT: Malaria transmission has been substantially reduced across Africa through the distribution of long-lasting insecticidal nets (LLINs). However, the emergence of insecticide resistance within mosquito vectors risks jeopardizing the future efficacy of this control strategy. The severity of this threat is uncertain because the consequences of resistance for mosquito fitness are poorly understood: while resistant mosquitoes are no longer immediately killed upon contact with LLINs, their transmission potential may be curtailed because of longer-term fitness costs that persist beyond the first 24 h after exposure. Here, we used a Bayesian state-space model to quantify the immediate (within 24 h of exposure) and delayed (>24 h after exposure) impact of insecticides on daily survival and malaria tr

SUBMITTER: Viana M 

PROVIDER: S-EPMC4987804 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature