Companion: a web server for annotation and analysis of parasite genomes.

ABSTRACT: Currently available sequencing technologies enable quick and economical sequencing of many new eukaryotic parasite (apicomplexan or kinetoplastid) species or strains. Compared to SNP calling approaches, de novo assembly of these genomes enables researchers to additionally determine insertion, deletion and recombination events as well as to detect complex sequence diversity, such as that seen in variable multigene families. However, there currently are no automated eukaryotic annotation pipelines offering the required range of results to facilitate such analyses. A suitable pipeline needs to perform evidence-supported gene finding as well as functional annotation and pseudogene detection up to the generation of output ready to be submitted to a public database. Moreover, no current tool inc

SUBMITTER: Steinbiss S 

PROVIDER: S-EPMC4987884 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature