SimpleSynteny: a web-based tool for visualization of microsynteny across multiple species.

ABSTRACT: Defining syntenic relationships among orthologous gene clusters is a frequent undertaking of biologists studying organismal evolution through comparative genomic approaches. With the increasing availability of genome data made possible through next-generation sequencing technology, there is a growing need for user-friendly tools capable of assessing synteny. Here we present SimpleSynteny, a new web-based platform capable of directly interrogating collinearity of local genomic neighbors across multiple species in a targeted manner. SimpleSynteny provides a pipeline for evaluating the synteny of a preselected set of gene targets across multiple organismal genomes. An emphasis has been placed on ease-of-use, and users are only required to submit FASTA files for their genomes and genes of inte

SUBMITTER: Veltri D 

PROVIDER: S-EPMC4987899 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature