Ontology highlight
ABSTRACT:
SUBMITTER: Zheng LL
PROVIDER: S-EPMC4987945 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Zheng Ling-Ling LL Xu Wei-Lin WL Xu Wei-Lin WL Liu Shun S Sun Wen-Ju WJ Li Jun-Hao JH Wu Jie J Yang Jian-Hua JH Qu Liang-Hu LH
Nucleic acids research 20160513 W1
tRNA-derived small RNA fragments (tRFs) are one class of small non-coding RNAs derived from transfer RNAs (tRNAs). tRFs play important roles in cellular processes and are involved in multiple cancers. High-throughput small RNA (sRNA) sequencing experiments can detect all the cellular expressed sRNAs, including tRFs. However, distinguishing genuine tRFs from RNA fragments generated by random degradation remains a major challenge. In this study, we developed an integrated web-based computing syste ...[more]