Time on timing: Dissociating premature responding from interval sensitivity in Parkinson's disease.

ABSTRACT:

Background

Parkinson's disease (PD) can cause impulsivity with premature responses, but there are several potential mechanisms. We proposed a distinction between poor decision-making and the distortion of temporal perception. Both effects may be present and interact, but with different clinical and pharmacological correlates.

Objectives

This study assessed premature responding during time perception in PD.

Methods

In this study, 18 PD patients and 19 age-matched controls completed 2 temporal discrimination tasks (bisection and trisection) and a baseline reaction-time task. Timing sensitivity and decision-making processes were quantified by response and response time. An extended version of the modified difference model was used to examine the precision of time represe

SUBMITTER: Zhang J 

PROVIDER: S-EPMC4988382 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature