Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis.

ABSTRACT: Cannabis use has been reported to induce long-lasting psychotic disorders and a dose-response relationship has been observed. We performed a systematic review of studies that investigate the association between the degree of cannabis consumption and psychosis and a meta-analysis to quantify the magnitude of effect. Published studies were identified through search of electronic databases, supplemented by manual searches of bibliographies. Studies were considered if they provided data on cannabis consumption prior to the onset of psychosis using a dose criterion (frequency/amount used) and reported psychosis-related outcomes. We performed random effects meta-analysis of individual data points generated with a simulation method from the summary data of the original studies. From 571 reference

SUBMITTER: Marconi A 

PROVIDER: S-EPMC4988731 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature