Pain sensitivity profiles in patients with advanced knee osteoarthritis.

ABSTRACT: The development of patient profiles to subgroup individuals on a variety of variables has gained attention as a potential means to better inform clinical decision making. Patterns of pain sensitivity response specific to quantitative sensory testing (QST) modality have been demonstrated in healthy subjects. It has not been determined whether these patterns persist in a knee osteoarthritis population. In a sample of 218 participants, 19 QST measures along with pain, psychological factors, self-reported function, and quality of life were assessed before total knee arthroplasty. Component analysis was used to identify commonalities across the 19 QST assessments to produce standardized pain sensitivity factors. Cluster analysis then grouped individuals who exhibited similar patterns of standar

SUBMITTER: Frey-Law LA 

PROVIDER: S-EPMC4988908 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature