Using Dendritic Heat Maps to Simultaneously Display Genotype Divergence with Phenotype Divergence.

ABSTRACT: The advancement of techniques to visualize and analyze large-scale sequencing datasets is an area of active research and is rooted in traditional techniques such as heat maps and dendrograms. We introduce dendritic heat maps that display heat map results over aligned DNA sequence clusters for a range of clustering cutoffs. Dendritic heat maps aid in visualizing the effects of group differences on clustering hierarchy and relative abundance of sampled sequences. Here, we artificially generate two separate datasets with simplified mutation and population growth procedures with GC content group separation to use as example phenotypes. In this work, we use the term phenotype to represent any feature by which groups can be separated. These sequences were clustered in a fractional identity range

SUBMITTER: Kellom M 

PROVIDER: S-EPMC4990276 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature