Percutaneous Epicardial Pacing using a Novel Insulated Multi-electrode Lead.

ABSTRACT:

Introduction

Epicardial cardiac resynchronization therapy (CRT) permits unrestricted electrode positioning. However, this requires surgical placement of device leads and the risk of unwanted phrenic nerve stimulation. We hypothesized that shielded electrodes can capture myocardium without extracardiac stimulation.

Methods

In 6 dog and 5 swine experiments, we used a percutaneous approach to access the epicardial surface of the heart, and deploy novel leads housing multiple electrodes with selective insulation. Bipolar pacing thresholds at prespecified sites were tested compare electrode threshold data both facing towards and away from the epicardial surface.

Results

In 151 paired electrode recordings (70 in 6 dogs; 81 in 5 swine), thresholds facing myocardium were lowe

SUBMITTER: Syed FF 

PROVIDER: S-EPMC4991355 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature