Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma.

ABSTRACT: Anti-tetanus antibodies in biological samples are typically detected using an enzyme-linked immunosorbent assay based on toxoided tetanus neurotoxin as antigen. We demonstrate that recombinantly produced fragment C of the toxin heavy chain is an effective alternative antigen for assessment of tetanus-immune status in plasma samples.

SUBMITTER: Ramakrishnan G 

PROVIDER: S-EPMC4991549 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature