Neuropsychological Profile of "Cognitive Frailty" Subjects in MAPT Study.

ABSTRACT:

Objectives

An international group proposed the existence of "cognitive frailty", a condition defined by simultaneous presence of physical frailty and cognitive impairment in the absence of dementia. The objective was to compare the neuropsychological profiles in subgroups of elders differentiated across their physical frailty (Fried phenotype) and cognitive status (Clinical Dementia Rating score) to characterize the "cognitive frailty" entity.

Method

We studied baseline characteristics of 1,617 subjects enrolled in Multidomain Alzheimer Disease Preventive Trial (MAPT). Included subjects were aged 70 years or older and presented at least 1 of the 3 following clinical criteria: (1) Memory complaint spontaneously reported to a general practitioner, (2) limitation in one instrum

SUBMITTER: Delrieu J 

PROVIDER: S-EPMC4991881 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature