Psychosis Prevention: A Modified Clinical High Risk Perspective From the Recognition and Prevention (RAP) Program.

ABSTRACT:

Objective

Early intervention and prevention of psychosis remain a major challenge. Prediction would be greatly advanced with improved ability to identify individuals at true risk, which, at present, is moderate at best. The authors tested a modified strategy to improve prediction by selecting a more homogeneous high-risk sample (attenuated positive symptom criteria only, age range of mid-teens to early 20s) than is currently standard, combined with a systematic selection of neurodevelopmental deficits.

Method

A sample of 101 treatment-seeking adolescents (mean age, 15.9 years) at clinical high risk for psychosis were followed clinically for up to 5 years (mean follow-up time, 3.0 years, SD=1.6). Adolescents were included only if they exhibited one or more attenuated positive

SUBMITTER: Cornblatt BA 

PROVIDER: S-EPMC4993209 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature