Prevention of Heat Stress Adverse Effects in Rats by Bacillus subtilis Strain.

ABSTRACT: This study was designed to evaluate the protective effect of the Bacillus subtilis strain against complications related to heat stress. Thirty-two Sprague-Dawley rats were used in this study. Animals were orally treated twice a day for two days with B. subtilis BSB3 strain or PBS. The next day after the last treatment, each group was divided and two experimental groups (one treated with PBS and one treated with B. subtilis) were placed at 45 (o)C for 25 min. Two control groups stayed for 25 min at room temperature. All rats were euthanized and different parameters were analyzed in all groups. Adverse effects of heat stress are registered by the decrease of villi height and total mucosal thickness in the intestinal epithelium; translocation of bacteria from the lumen; increased vesiculation

SUBMITTER: Sorokulova I 

PROVIDER: S-EPMC4993440 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature