Differences in Serum Human Chorionic Gonadotropin Rise in Early Pregnancy by Race and Value at Presentation.

ABSTRACT:

Objective

To assess whether variation in serum human chorionic gonadotropin (hCG) measures, used to assess early gestation viability, are associated with differences in clinical presentation and patient factors.

Method

This retrospective cohort study included 285 women with first-trimester pain and bleeding and a pregnancy of unknown location for whom a normal intrauterine pregnancy was ultimately confirmed. Serial samples were collected at three U.S. sites and hCG changes were analyzed for differences by race, ethnicity, and clinical factors. A nonlinear, mixed-effects regression model was used assuming a random subject shift in the time axis.

Results

The hCG rise in symptomatic women with ongoing intrauterine pregnancy differs by patient factors and level at present

SUBMITTER: Barnhart KT 

PROVIDER: S-EPMC4993627 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature