Serum neutrophil gelatinase-associated lipocalin and resistin are associated with dengue infection in adults.

ABSTRACT:

Background

Dengue is a major health problem in tropical areas, including Taiwan. Dengue virus infection affects various types of cells and results in elevation of serum inflammatory molecules. Because these molecules may be associated with dengue virus infection, the aim of this study was to identify novel molecules in febrile patients with dengue infection. In addition, we determined whether these molecules were correlated with the count of leukocytes and platelets.

Methods

Febrile adults (Age >18 years old) who presented to the emergency department and were confirmed dengue virus infection were enrolled in this study. Serum from dengue patients and healthy controls was collected and serum level of sepsis-associated inflammatory molecules was measured by Luminex assay.

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SUBMITTER: Liu KT 

PROVIDER: S-EPMC4994210 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature