First Prospective Cohort Study of Diabetic Retinopathy from Sub-Saharan Africa: High Incidence and Progression of Retinopathy and Relationship to Human Immunodeficiency Virus Infection.

ABSTRACT:

Purpose

To describe the prevalence, incidence, and progression of retinopathy and to report associations with demographic, clinical, and biochemical variables in people with diabetes in Southern Malawi.

Design

Prospective cohort study.

Participants

Subjects were systematically sampled from 2 primary care diabetes clinics.

Methods

We performed the first prospective cohort study of diabetic retinopathy from Sub-Saharan Africa over 24 months. Visual acuity, glycemic control, blood pressure, human immunodeficiency virus (HIV) status, urine albumin-to-creatinine ratio, hemoglobin, and lipids were assessed. Retinopathy was graded at an accredited reading center using modified Wisconsin grading of 4-field mydriatic photographs.

Main outcome measures

Incidence o

SUBMITTER: Burgess PI 

PROVIDER: S-EPMC4994575 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature