A systematic review of ethical issues in vaccine studies involving pregnant women.

ABSTRACT:

Background

Immunization during pregnancy can provide protection for mother and child. However, there have been only a limited number of studies documenting the efficacy and safety of this strategy.

Aims

To determine the extent and nature of subject matter related to ethics in maternal immunization by systematically documenting the spectrum of ethical issues in vaccine studies involving pregnant women.

Method

We conducted a systematic literature review of published works pertaining to vaccine and therapeutic studies involving pregnant women through searches of PubMed, EMBASE, Web of Science, the Cochrane Database, and ClinicalTrials.gov. We selected literature meeting the inclusion criteria published between 1988 and June 2014. We systematically abstracted subject matt

SUBMITTER: Beeler JA 

PROVIDER: S-EPMC4994733 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature