Association between Birth Characteristics and Cardiovascular Autonomic Function at Mid-Life.

ABSTRACT:

Background

Low birth weight is associated with an increased risk of cardiovascular diseases in adulthood. As abnormal cardiac autonomic function is a common feature in cardiovascular diseases, we tested the hypothesis that low birth weight may also be associated with poorer cardiac autonomic function in middle-aged subjects.

Methods

At the age of 46, the subjects of the Northern Finland Birth Cohort 1966 were invited to examinations including questionnaires about health status and life style and measurement of vagally-mediated heart rate variability (rMSSD) from R-R intervals (RRi) and spontaneous baroreflex sensitivity (BRS) in both seated and standing positions. Maternal parameters had been collected in 1965-1966 since the 16th gestational week and birth variables immediat

SUBMITTER: Perkiomaki N 

PROVIDER: S-EPMC4994955 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature