Evaluating early-life asthma definitions as a marker for subsequent asthma in an electronic medical record setting.

ABSTRACT:

Background

Case definitions for asthma incidence in early life vary between studies using medical records to define disease. This study assessed the impact of different approaches to using medical records on estimates of asthma incidence by age 3 and determined the validity of early-life asthma case definitions in predicting school-age asthma.

Methods

Asthma diagnoses and medications by age 3 were used to classify 7103 children enrolled in Kaiser Permanente Georgia according to 14 definitions of asthma. School-age asthma was defined as an asthma diagnosis between ages 5 and 8. Sensitivity (probability of asthma by age 3 given school-age asthma), specificity (probability of no asthma by age 3 given no school-age asthma), positive and negative predictive values (probability of

SUBMITTER: Pennington AF 

PROVIDER: S-EPMC4995117 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature