Characterizing cognitive performance in a large longitudinal study of aging with computerized semantic indices of verbal fluency.

ABSTRACT: A computational approach for estimating several indices of performance on the animal category verbal fluency task was validated, and examined in a large longitudinal study of aging. The performance indices included the traditional verbal fluency score, size of semantic clusters, density of repeated words, as well as measures of semantic and lexical diversity. Change over time in these measures was modeled using mixed effects regression in several groups of participants, including those that remained cognitively normal throughout the study (CN) and those that were diagnosed with mild cognitive impairment (MCI) or Alzheimer's disease (AD) dementia at some point subsequent to the baseline visit. The results of the study show that, with the exception of mean cluster size, the indices showed si

SUBMITTER: Pakhomov SVS 

PROVIDER: S-EPMC4996679 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature