Quality of Life in Children With Advanced Cancer: A Report From the PediQUEST Study.

ABSTRACT:

Context

Modifiable factors of health-related quality of life (HRQOL) are poorly described among children with advanced cancer. Symptom distress may be an important factor for intervention.

Objectives

We aimed to describe patient-reported HRQOL and its relationship to symptom distress.

Methods

Prospective, longitudinal data from the multicenter Pediatric Quality of Life and Symptoms Technology study included primarily patient-reported symptom distress and HRQOL, measured at most weekly with the Memorial Symptoms Assessment Scale and Pediatric Quality of Life inventory, respectively. Associations were evaluated using linear mixed-effects models adjusting for sex, age, cancer type, intervention arm, treatment intensity, and time since disease progression.

Results

SUBMITTER: Rosenberg AR 

PROVIDER: S-EPMC4996729 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature