Sugar-sweetened beverage consumption and genetic predisposition to obesity in 2 Swedish cohorts.

ABSTRACT:

Background

The consumption of sugar-sweetened beverages (SSBs), which has increased substantially during the last decades, has been associated with obesity and weight gain.

Objective

Common genetic susceptibility to obesity has been shown to modify the association between SSB intake and obesity risk in 3 prospective cohorts from the United States. We aimed to replicate these findings in 2 large Swedish cohorts.

Design

Data were available for 21,824 healthy participants from the Malmö Diet and Cancer study and 4902 healthy participants from the Gene-Lifestyle Interactions and Complex Traits Involved in Elevated Disease Risk Study. Self-reported SSB intake was categorized into 4 levels (seldom, low, medium, and high). Unweighted and weighted genetic risk scores (GRSs) w

SUBMITTER: Brunkwall L 

PROVIDER: S-EPMC4997292 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature