Evaluating the risk of ovarian cancer before surgery using the ADNEX model: a multicentre external validation study.

ABSTRACT:

Background

The International Ovarian Tumour Analysis (IOTA) group have developed the ADNEX (The Assessment of Different NEoplasias in the adneXa) model to predict the risk that an ovarian mass is benign, borderline, stage I, stages II-IV or metastatic. We aimed to externally validate the ADNEX model in the hands of examiners with varied training and experience.

Methods

This was a multicentre cross-sectional cohort study for diagnostic accuracy. Patients were recruited from three cancer centres in Europe. Patients who underwent transvaginal ultrasonography and had a histological diagnosis of surgically removed tissue were included. The diagnostic performance of the ADNEX model with and without the use of CA125 as a predictor was calculated.

Results

Data from 610 women

SUBMITTER: Sayasneh A 

PROVIDER: S-EPMC4997550 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature