Anticancer Platelet-Mimicking Nanovehicles.

ABSTRACT: A core-shell nanovehicle coated with a platelet membrane (PM) is developed for targeted and site-specific delivery of an extracellularly active drug and an intracellular functional small-molecular drug, leading to enhanced antitumor efficacy. This PM-coated nanovehicle can also effectively eliminate the circulating tumor cells in vivo and inhibit development of tumor metastasis.

SUBMITTER: Hu Q 

PROVIDER: S-EPMC4998740 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature