Macular Morphology and Visual Acuity in the Second Year of the Comparison of Age-Related Macular Degeneration Treatments Trials.

ABSTRACT:

Purpose

To describe the association between morphologic features on fundus photography (FP), fluorescein angiography (FA), and optical coherence tomography (OCT) and visual acuity (VA) in the second year of the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).

Design

Prospective cohort study within a randomized clinical trial.

Participants

Participants in the CATT.

Methods

Study eye eligibility required angiographic and OCT evidence of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) and VA between 20/25 and 20/320. Treatment was assigned randomly to ranibizumab or bevacizumab with 3 different dosing regimens over a 2-year period.

Main outcome measures

Fluid type, location, and thickness; retin

SUBMITTER: Sharma S 

PROVIDER: S-EPMC4998967 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature