Association between BHMT gene rs3733890 polymorphism and cancer risk: evidence from a meta-analysis.

ABSTRACT:

Background and objective

The gene betaine-homocysteine methyltransferase (BHMT) has drawn much attention during the past decades. An increasing number of clinical and genetic investigations have supposed that BHMT rs3733890 polymorphism might be associated with risk of breast cancer and ovarian cancer. As no consistent conclusion has been achieved, we conducted an up-to-date summary of BHMT rs3733890 polymorphism and cancer risk through a meta-analysis.

Materials and methods

The articles were collected from PubMed, Google Scholar, and CNKI (Chinese) databases up to December 2015. Then, the correlations were determined by reading the titles and abstracts and by further reading the full text to filter the unqualified articles. Odds ratio (OR) and the corresponding 95% confiden

SUBMITTER: Xu Y 

PROVIDER: S-EPMC5001659 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature