Pre-existing and Postoperative Intimal Hyperplasia and Arteriovenous Fistula Outcomes.

ABSTRACT:

Background

The contribution of intimal hyperplasia (IH) to arteriovenous fistula (AVF) failure is uncertain. This observational study assessed the relationship between pre-existing, postoperative, and change in IH over time and AVF outcomes.

Study design

Prospective cohort study with longitudinal assessment of IH at the time of AVF creation (pre-existing) and transposition (postoperative). Patients were followed up for up to 3.3 years.

Setting & participants

96 patients from a single center who underwent AVF surgery initially planned as a 2-stage procedure. Veins and AVF samples were collected from 66 and 86 patients, respectively. Matched-pair tissues were available from 56 of these patients.

Predictors

Pre-existing, postoperative, and change in IH over time.<

SUBMITTER: Tabbara M 

PROVIDER: S-EPMC5002252 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature