Recent and Long-Term Selection Across Synonymous Sites in Drosophila ananassae.

ABSTRACT: In Drosophila, many studies have examined the short- or long-term evolution occurring across synonymous sites. Few, however, have examined both the recent and long-term evolution to gain a complete view of this selection. Here we have analyzed Drosophila ananassae DNA polymorphism and divergence data using several different methods, and have identified evidence of positive selection favoring preferred codons in both recent and long-term evolutionary time scale. Further in D. ananassae, the strength of selection for preferred codons was stronger on the X chromosome compared to the autosomes. We show that this stronger selection is not due to higher gene expression of X-linked genes. Analysis of the selectively neutral introns indicated that the X chromosome also had a preference for GC over

SUBMITTER: Choi JY 

PROVIDER: S-EPMC5002260 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature